Daptacel (Diptheria and Tetanus Toxoids and Acellular Pertussis Vaccine Absorbed

Is the DAPTACEL Vaccine Safe?

DAPTACEL vaccine has been demonstrated to be safe and well tolerated.7,8,10

• The rates of adverse reactions to DAPTACEL vaccine (n= 2587) were similar to the DT placebo-control vaccine (n=2574). 7,8

• A well-tolerated vaccine may help parents comply with immunization recommendations for their children.6,8

• There are risks associated with all vaccines. Local and systemic adverse reactions may include redness, swelling, pain or tenderness at the injection site, fever, irritability, prolonged crying, drowsiness, vomiting, and anorexia. Other local and systemic adverse reactions may occur.

Remember, immunizations are one of the most important ways parents can protect their children against diseases like pertussis. Before the pertussis vaccine was developed, over 260,000 cases of pertussis and 9000 deaths due to pertussis were reported each year in the United States.8,9 But thanks to vaccination, millions of children are protected from serious, life-threatening diseases like pertussis.

Get more information:

Protection Safety Packaging Prescribing Information

6. American Academy of Pediatrics Committee on Infectious Diseases. Recommended childhood immunization schedule—United States, 2002. Pediatrics. 2002;109:162-164.
7. DAPTACEL Vaccine Prescribing Information, March 2003.
8. Gustafsson L, Hallander HO, Ohio P, et al. A controlled trial of two-component acellular, aa five component acellular, and a wholecell pertussis vaccine. N Engl J Med. 1966;334:349-355.
9. WHO meeting on case definition of pertussis: Geneva, 10-11 January 1991. Geneva, Switzerland: World Health Organization: 1991:4-5. issue MIM/EPI/PERT/91.1.
10. Decker MD, Edwards KM, Steinhoff MC, et al. Comparison of 13 acellular pertussis vaccines: adv erse reactions. Pediatrics. 1995; 96 (suppl):557-566.


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Safety Information

DAPTACEL® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) is a vaccine given to infants and children 6 weeks through 6 years (prior to 7th birthday) to prevent 3 serious diseases: diphtheria, tetanus (lockjaw), and pertussis (whooping cough). As with any vaccine, vaccination with DAPTACEL vaccine may not protect 100% of individuals. There are risks associated with all vaccines. The most common side effects with DAPTACEL vaccine are redness, swelling, and soreness or tenderness where the injection was given; fever, fussiness, and crying more than usual. Other side effects may occur. DAPTACEL vaccine should not be given to children who, after a previous dose of the vaccine, have had a serious allergic reaction (anaphylactic reaction) or encephalopathy not attributable to another cause.

For more information about DAPTACEL vaccine, refer to the Patient Information on DAPTACEL.com and talk to your child's health-care provider.